Can You Mix L-Glutamine with Coffee? Maybe Not the Best Idea

The idea of mixing L-Glutamine with coffee might seem unusual, but many people wonder if it’s a feasible option. 

After all, why not take your supplements with your daily cup of coffee? It’s convenient if nothing else.

Well, that may not be the case after all.

In this article, we’ll explore the compatibility of L-Glutamine and coffee, along with the best ways to consume this popular supplement. So can you mix l-glutamine with coffee? Let’s find out.

Is it Ok to Mix L-Glutamine with Coffee?

The opinion on this is mixed. Some would claim that it isn’t okay to mix L-glutamine with coffee, and others say you don’t need to worry about anything.

From what we know so far, it would seem that it is not OK to mix L-Glutamine with hot coffee. [1]


Well, the heat from the coffee might cause L-glutamine to degrade, potentially reducing its effectiveness. [2] We say potentially because many amino acids can easily withstand temperatures of up to 120 degrees Celsius or 250 Fahrenheit. 

But if you want to be safe, consider letting the coffee cool down slightly before mixing in the L-Glutamine powder, or just mix it with iced coffee.

Despite some concerns about heat, L-glutamine is a versatile amino acid supplement that can be easily combined with various liquids, including coffee – as long as it is not scorching hot.

Would Mixing L-Glutamine with Coffee Lead to Any Additional Benefits?

While there are no specific benefits associated with mixing L-Glutamine and coffee, combining the two can simplify your supplement routine and save time. 

Both L-glutamine and coffee are known for their individual benefits – L-glutamine for gut health and immune support and coffee for its cognitive and energy-boosting effects. [3]

So, consuming them together can help you enjoy their respective advantages and avoid washing another glass or a cup.

As for synergistic effects – there aren’t any that we know of. 

So, it basically comes down to convenience.

Is the Morning the Best Time to Take L-Glutamine?

Taking L-glutamine in the morning on an empty stomach might be beneficial. That said, if you’re pairing it with coffee – you probably shouldn’t do that on an empty stomach as coffee and an empty stomach aren’t the best of pals.

That said, the optimal time for L-glutamine intake varies on individual needs, and it really isn’t set in stone. 

Ultimately, as long as you get your prescribed dose in – you shouldn’t have to worry about timing.

What is a Good Dosage of L-Glutamine?

A typical dosage of L-Glutamine ranges from 5 to 10 grams per day, usually spread out in two to three doses, depending on individual requirements and the desired effects.

However, some individuals have been known to supplement with 50 grams of glutamine each day.

How much you’ll need will also probably vary depending on your circumstances and needs.

But, we must say, if you’re thinking about glutamine because you want to improve your performance in the gym or post-workout recovery  – we would suggest you stop.

It is quite likely it won’t help you at all. [4]

Which Liquids are Best for Mixing L-Glutamine Powder?

L-glutamine powder can be mixed with various liquids, but the best liquid for mixing L-glutamine powder is water.

But, if you wanted to try mixing it with smoothies, juice, or even coffee – you could. 

Just remember what we said about excessive heat and its effects on glutamine’s effectiveness. 

But in the end, feel free to experiment with different liquids to find the one that best suits your taste preferences and nutritional goals.

Can You Mix L-Glutamine with Protein Shakes or Foods?

Absolutely. You can mix L-glutamine with protein shakes or food.

Mixing L-glutamine with protein shakes or incorporating it into foods like oatmeal, yogurt, or smoothies is a convenient way to include this supplement in your diet. 

If you wanted to – you could even sprinkle it on top of a steak or a salad.

Now, keep in mind that glutamine tends to be a bit sweet, so if you’re not a fan of that – maybe keep it limited to non-savory stuff.

Do You Really Need L-Glutamine Supplements?

No, you really don’t need L-glutamine supplements if your goal is to push yourself in the gym.

Despite aggressive marketing, there’s pretty much nothing glutamine can do to make you lift more, grow bigger, or recover faster.

Now, if you’re supplementing because you have issues with your stomach – by all means – go for it. There’s a good chance it could help with that.

Also, medical issues aside, we have to remember that many foods, such as meat, fish, and dairy, are naturally rich in L-glutamine, and if you just need 5 grams – most of us already eat as much. [5]


In conclusion, mixing L-glutamine with coffee is a viable option for those looking to simplify their supplement routine and who like to drink their coffee cold or warm.

Hot coffee lovers? Probably shouldn’t mix the two.

You’re already dealing with a semi-effective supplement, so you probably don’t want to make things worse.

What to Read Next

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