The 7 Best PhosphatidylSerine Supplements

Hey there! Just a quick heads up that we use affiliate links from Amazon and other retailers. So if you choose to make a purchase, we may earn a small commission at no extra cost to you. We greatly appreciate your support!

Are you looking to get a cognitive boost and lower your stress levels? I was too, which had me searching for the best phosphatidylserine supplements. 

As someone who’s a bit of a supplement fanatic, I don’t like to stop until I’ve found the best product. So I’ve tried several phosphatidylserine supplements for the past year or so. Today, I’m bringing you my results and breaking down the best ones on the market. Let’s get started. 

1. Best Overall: Deal Supplement PhosphatidylSerine Capsules

Deal Supplement Phosphatidylserine

The brand is called Deal Supplement, and well, I found this one to be the best deal on the market when it comes to phosphatidylserine. 

Out of the phosphatidylserine supplements, it has one of the highest dosages (400mg) and the lowest cost per serving ($0.23 per serving). The phosphatidylserine in it is also derived from sunflower lecithin, which is what you want to see. It ensures it provides a high potency and effective results. 

Was this one effective? Yes, it was. In fact, I found it to be the sweet spot for dosage, at least for me. 400mg of phosphatidylserine seems to keep me calm and focused when I’m working. I don’t feel bogged down by brain fog, and I have a bit of extra drive to keep going. 

Plus, I’ve found it’s not a bad supplement to take post-workout, especially when I train at night. We all can get pretty hyped up from our training sessions. That usually causes me to not be able to fall asleep as easily after my nighttime training sessions. So I take some phosphatidylserine to help me relax. 

The one thing to note with this one is it isn’t vegan-friendly. Specifically, the capsule they put it in isn’t vegan. So if you have vegan dietary restrictions, this isn’t the one for you. 

Overall, I love this one. It’s a great deal; other than not being vegan-friendly, you can’t go wrong with it. 

Pros

  • Optimal dosage
  • Low cost-per-serving for capsules
  • Comes in a high-quality bottle
  • 3rd party tested
  • Nut, dairy, & gluten-free
  • Sourced from sunflower lecithin

Cons

  • Not vegan-friendly

Overall Rating: 9.6/10

  • Dosage: 10/10
  • Cost per serving: 10/10
  • Effectiveness: 10/10
  • Packaging: 9/10
  • Ease of use: 10/10
  • Ingredient sourcing: 9/10

2. Best Vegan PhosphatidylSerine: Nutricost PhosphatidylSerine Capsules

Nutricost Phosphatidylserine

I also wanted to ensure everyone with vegan or plant-based dietary needs was covered. Of the certified vegan products, I found the Nutricost PhosphatidylSerine capsules to be the best quality. 

These have a very reasonable cost per serving ($0.28 per serving) and an optimal dosage (400mg per serving). You really can’t go wrong with these capsules. 

I even considered making them the best overall product on this list since they satisfy pretty much all dietary restrictions and needs. But I know some are very concerned about getting the optimal cost per serving out of their supplements, as am I, which dropped these down a bit. 

Additionally, this phosphatidylserine is also sourced from sunflower lecithin, which is better than the soy variety, in my opinion. 

Pros

  • Certified vegan
  • Optimal dosage
  • Good cost-per-serving
  • Soy-free and gluten-free
  • Sourced from sunflower lecithin

Cons

  • The bottle could be higher quality

Overall Rating: 9.4/10

  • Dosage: 10/10
  • Cost per serving: 9.5/10
  • Effectiveness: 10/10
  • Packaging: 7/10
  • Ease of use: 10/10
  • Ingredient sourcing: 10/10

3. Best PhosphatidylSerine Powder: Bulk Supplements PhosphatidylSerine Powder

Bulk Supplements Phosphatidylserine

It’s honestly pretty tough to find a good phosphatidylserine powder. Thankfully, Bulk Supplements came through with this one. I never hesitate to recommend them because they’re a brand known for reliable sourcing and fair prices. 

As far as effectiveness goes, this product absolutely worked well. The powder is very high-quality. And the great thing about powdered supplements is that you can adjust the dosage to your needs much easier. 

The dosing on the label is a bit confusing. It says if you take 500mg, you’ll get 100mg of phosphatidylserine. Essentially, it’s similarly dosed as capsule variations, just labeled weirdly. 

You’ll see nearly every capsule version on this list has phosphatidylserine 20% on the label. That essentially means it’s at 20% potency. So when you take a 400mg capsule at 20% potency, you’re actually getting 80mg of phosphatidylserine.

Bulk Supplements is actually labeling it honestly for the amount of pure phosphatidylserine you’re getting. It’s a pretty good deal since you get 100mg of pure phosphatidylserine per serving. And it comes in at around $0.23 or less per serving, depending on how big of a bag you buy. 

The phosphatidylserine in this one is sourced from soy. So if you have soy sensitivities, this won’t be for you. I also found the powder to be a bit hard to mix, so make sure to stir/shake thoroughly. 

Pros

  • Reputable company
  • Effective
  • Honest labeling 
  • Great cost per serving

Cons

  • Sourced from soy
  • Hard to mix

Overall Rating: 9.1/10

  • Dosage: 10/10
  • Cost per serving: 10/10
  • Effectiveness: 10/10
  • Packaging: 8/10
  • Ease of use: 8/10
  • Ingredient sourcing: 9/10

4. Best PhosphatidylSerine Gummies: Lifeable PhosphatidylSerine Gummies

Lifeable Phosphatidylserine Gummies

I know a lot of people look for gummy versions of supplements whenever possible. After all, mixing powder and swallowing pills can be annoying or a less than enjoyable supplement-taking experience sometimes. So why not take a fun gummy instead? 

Of the ones I tried, I liked the flavor of these the best. Unfortunately, the flavor still isn’t great. It’s a very sugary raspberry taste. But they’re definitely edible. 

Be aware that these are also marketed as a supplement for kids, but adults love gummies too. And you should have no problems taking these as an adult. 

I would also triple or quadruple the recommended serving if you’re an adult taking them to get effective results. That brings them up to $1.26-$1.72 per serving. So it’s really not the most optimal way to spend your money. But if you like gummies, they’re the way to go.

Pros

  • Easy to use
  • Sourced from sunflower lecithin
  • Well-packaged
  • Vegetarian 
  • Gluten-free

Cons

  • Pricey
  • Not the best flavor
  • Low serving count per bottle
  • Not vegan friendly

Overall Rating: 8.2/10

  • Dosage: 8/10
  • Cost per serving: 5/10
  • Effectiveness: 10/10
  • Packaging: 10/10
  • Ease of use: 10/10
  • Ingredient sourcing: 9/10
  • Flavor: 6/10

5. Best Cognitive Formula with PhosphatidylSerine: Type Zero PhosphatidylSerine Brain Support 

Type Zero Phosphatidylserine

This formula should do the trick if you want a bit more of a cognitive boost. Each serving contains:

  • 400mg Phosphatidylserine
  • 300mg Alpha-GPC
  • 200mcg Huperzine A

Out of the cognitive formulas with phosphatidylserine, I like this one the best because it doesn’t overcomplicate it. Adding alpha-GPC and huperzine provides two well-studied compounds for focus and memory support. Plus, all of these compounds are effectively dosed. 

When I took it, I found my ability to focus at work went into overdrive. It’s not a feeling I necessarily want to have all the time, but if I’m a bit tired or sluggish, having an extra kick isn’t a bad thing. I just wouldn’t take this one every day. 

At a cost per serving of $0.40, this one is a great value for the compounds in it. 

The phosphatidylserine in it is even sourced from sunflower, and it’s vegan-friendly, so you’re all good there. 

Other than not necessarily being a daily-use product, I don’t have anything bad to say about this one. 

Pros

  • Effectively dosed
  • Big focus and memory boost
  • Phosphatidylserine sourced from sunflower lecithin
  • Vegan-friendly
  • Well-packaged
  • 3rd party tested

Cons

  • May not be one you want to use daily

Overall Rating: 9.6/10

  • Dosage: 10/10
  • Cost per serving: 9/10
  • Effectiveness: 10/10
  • Packaging: 9/10
  • Ease of use: 10/10
  • Ingredient sourcing: 10/10

6. Best Extra Strength PhosphatidylSerine: NOW Supplements PhosphatidylSerine

NOW Phosphatidylserine

When I first tried this one, I didn’t expect it to be much different than many of the other 300mg capsules on the market. Then the “extra strength” part kicked in. I didn’t realize this was a full 300mg of pure phosphatidylserine and not 300mg at 20% potency like most other capsules are. I actually had trouble sleeping the first night because of the extra strength. 

This one is too powerful for my needs. However, it gets good reviews on Amazon and other places from others who have used it. So if you don’t see effects from other phosphatidylserine capsules, try this one out. It might be the right fit for your needs. 

Pros

  • Pure and potent dosage
  • GMP Certified
  • Only need to take one capsule to get a full dose
  • Well-packaged
  • Reasonable cost per serving

Cons

  • May be too highly dosed for some 
  • Derived from soy (watch out if you have soy sensitivities)

Overall Rating: 9/10

  • Dosage: 10/10
  • Cost per serving: 8.5/10
  • Effectiveness: 9/10
  • Packaging: 9/10
  • Ease of use: 10/10
  • Ingredient sourcing: 8/10

7. Best Low-Dose PhosphatidylSerine: Doctor’s Best PhosphatidylSerine

Doctor's Best Phosphatidylserine

On the opposite end of the spectrum, if you find many products are too highly-dosed for your needs, give this one a try. 

The package recommends taking 3 of the 100mg capsules per day for effective dosage. That’s what I found I needed to feel the full effects. But everyone responds to supplements differently. If you respond well to 100mg, that’s all you need to take.  

If you’re taking the lowest-possible dose, then this is a great option to achieve that. However, if you bump up to the full 300mg dose, then the cost-per-serving is much worse than other options.

These are also derived from soy, which isn’t my favorite choice. However, I definitely felt the effects, so I don’t have much in complaints. 

Pros

  • A good option for lower doses
  • Quality packaging
  • Effective 
  • Vegan

Cons

  • Higher cost per serving
  • Derived from soy

Overall Rating: 8.1/10

  • Dosage: 8/10
  • Cost per serving: 5/10
  • Effectiveness: 9/10
  • Packaging: 9/10
  • Ease of use: 10/10
  • Ingredient sourcing: 8/10

Conclusion

There you go—all 7 of the best options for phosphatidylserine supplementation. I’m confident you can find a great choice with one of the options on this list. Soon your brain power will be off the charts, and you’ll be stress-free at the same time.

Thanks for reading!   

Share This Post
Pierce Reiten
Pierce Reiten

Pierce Reiten is an NASM certified personal trainer with over a decade of experience in the gym. He's passionate about providing information to help you improve your fitness and life.

Articles: 28

Leave a Reply

Your email address will not be published. Required fields are marked *